Bone Abstracts

Anorexia nervosa (AN) occurs in 0.2–1% of adolescent girls and is characterized by physiological and adaptive changes in the various endocrine axes. Changes also occur in many hormones secreted or regulated by fat (a reflection of energy stores) that can impact bone. The physiological changes observed in various endocrine axes in AN in turn cause impaired bone accrual rates, low bone density (associated with increased marrow fat) and impaired bone microarchitecture. This ...

Anorexia nervosa (AN) is reported in 0.2–1% of adolescent girls and is characterized by physiological and adaptive changes in various endocrine axes. Alterations also occur in many hormones secreted or regulated by fat (a reflection of energy stores) that can impact bone. Physiological endocrine changes in AN in turn lead to impaired bone accrual rates, low bone density, impaired bone microarchitecture, decreased bone strength, and an increased risk for fracture. In addit...

Biographical DetailsDr Madhusmita Misra is a full Professor of Pediatrics at Harvard Medical School and a Pediatric Endocrinologist at Massachusetts General Hospital in Boston, Massachusetts. She directs the fellowship training program in Pediatric Endocrinology at Massachusetts General Hospital, and has a Masters in Public Health from the Harvard School of Public Health. Dr M Misra’...